RETN / Resistin Antibody
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, E |
---|---|
Primary Accession | Q9HD89 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 11kDa |
Dilution | IHC-P (10 µg/ml), WB (0.2-0.4 µg/ml), |
Gene ID | 56729 |
---|---|
Other Names | Resistin, Adipose tissue-specific secretory factor, ADSF, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, RETN, FIZZ3, HXCP1, RSTN |
Target/Specificity | Human Resistin |
Reconstitution & Storage | Store Lyophilized at room temperature up to 1 month; Reconstituted for up to two weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles. |
Precautions | RETN / Resistin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RETN |
---|---|
Synonyms | FIZZ3, HXCP1, RSTN |
Function | Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity). Potentially links obesity to diabetes (By similarity). Promotes chemotaxis in myeloid cells (PubMed:15064728). |
Cellular Location | Secreted {ECO:0000250|UniProtKB:Q99P87}. |
Tissue Location | Expressed in white adipose tissue (at protein level) (PubMed:11201732). Widely expressed, with particularly strong expression in lung, bone marrow, breast and peripheral blood (PubMed:15248836). Expressed strongly in bone marrow and at lower levels in lung, but not detected in other tissues (PubMed:15064728) Isoform 2 is detected in adipose tissue, bone marrow, brain, lung, peripheral blood, placenta and thymus (PubMed:15248836) |

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Provided below are standard protocols that you may find useful for product applications.
Background
Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.
References
Holcomb I.N.,et al.EMBO J. 19:4046-4055(2000).
Steppan C.M.,et al.Nature 409:307-312(2001).
Kubota T.,et al.Blood 96:3953-3957(2000).
Nohira T.,et al.Eur. J. Endocrinol. 151:151-154(2004).
Rajala M.W.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.

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