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ASCL3 Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - ASCL3 Antibody (Internal) ALS15392
    ASCL3 antibody (0.1 ug/ml) staining of Human Liver lysate (35 ug protein/ml in RIPA buffer).
    detail
  • IHC - ASCL3 Antibody (Internal) ALS15392
    Anti-ASCL3 antibody IHC of human brain, cortex.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9NQ33
Reactivity Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Calculated MW 21kDa
Dilution ELISA (1:8000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)
Additional Information
Gene ID 56676
Other Names Achaete-scute homolog 3, ASH-3, hASH3, Class A basic helix-loop-helix protein 42, bHLHa42, bHLH transcriptional regulator Sgn-1, ASCL3, BHLHA42, HASH3, SGN1
Target/Specificity Human ASCL3.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsASCL3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASCL3 (HGNC:740)
Synonyms BHLHA42, HASH3, SGN1
Function Transcriptional repressor. Inhibits myogenesis. Plays a role in progenitor cells which differentiate into ductal and acinar, but not myoepithelial, cell lineages in the salivary glands. Involved in the functions of the microvillar cells and Bowman's glands and probably, in a non-cell-autonomous manner, in the development or regeneration of a complete olfactory epithelium (OE).
Cellular Location Nucleus.
Tissue Location Widely expressed in fetal and adult tissues.
Citations (0)
citation

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Background

Transcriptional repressor. Inhibits myogenesis (By similarity).

References

Yoshida S.,et al.Dev. Biol. 240:517-530(2001).
Amid C.,et al.Cytogenet. Cell Genet. 93:284-290(2001).
Jonsson M.,et al.Genomics 84:859-866(2004).

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$ 467.50
Cat# ALS15392
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