ASCL3 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9NQ33 |
Reactivity | Human, Mouse, Rat |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 21kDa |
Dilution | ELISA (1:8000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml) |
Gene ID | 56676 |
---|---|
Other Names | Achaete-scute homolog 3, ASH-3, hASH3, Class A basic helix-loop-helix protein 42, bHLHa42, bHLH transcriptional regulator Sgn-1, ASCL3, BHLHA42, HASH3, SGN1 |
Target/Specificity | Human ASCL3. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | ASCL3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ASCL3 (HGNC:740) |
---|---|
Synonyms | BHLHA42, HASH3, SGN1 |
Function | Transcriptional repressor. Inhibits myogenesis. Plays a role in progenitor cells which differentiate into ductal and acinar, but not myoepithelial, cell lineages in the salivary glands. Involved in the functions of the microvillar cells and Bowman's glands and probably, in a non-cell-autonomous manner, in the development or regeneration of a complete olfactory epithelium (OE). |
Cellular Location | Nucleus. |
Tissue Location | Widely expressed in fetal and adult tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional repressor. Inhibits myogenesis (By similarity).
References
Yoshida S.,et al.Dev. Biol. 240:517-530(2001).
Amid C.,et al.Cytogenet. Cell Genet. 93:284-290(2001).
Jonsson M.,et al.Genomics 84:859-866(2004).
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