IDH3A Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P50213 |
Reactivity | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Horse, Bovine |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 40kDa |
Dilution | ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml) |
Gene ID | 3419 |
---|---|
Other Names | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, 1.1.1.41, Isocitric dehydrogenase subunit alpha, NAD(+)-specific ICDH subunit alpha, IDH3A |
Target/Specificity | Human IDH3A. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | IDH3A Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IDH3A (HGNC:5384) |
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Function | Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. |
Cellular Location | Mitochondrion. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
References
Kim Y.O.,et al.Biochem. J. 308:63-68(1995).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Choudhary C.,et al.Science 325:834-840(2009).
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