NAB2 Antibody (aa261-310)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q15742 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 57kDa |
Dilution | ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500-1:1000) |
Gene ID | 4665 |
---|---|
Other Names | NGFI-A-binding protein 2, EGR-1-binding protein 2, Melanoma-associated delayed early response protein, Protein MADER, NAB2, MADER |
Target/Specificity | NAB2 Antibody detects endogenous levels of total NAB2 protein. |
Reconstitution & Storage | Store at -20°C for up to one year. |
Precautions | NAB2 Antibody (aa261-310) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NAB2 |
---|---|
Synonyms | MADER |
Function | Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity). |
Cellular Location | Nucleus. Note=Isoform 2 is not localized to the nucleus. |
Tissue Location | Widely expressed at low levels. Highly expressed in melanoma cell lines |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity).
References
Svaren J.,et al.Mol. Cell. Biol. 16:3545-3553(1996).
Gerlinger M.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Kirsch K.H.,et al.Oncogene 12:963-971(1996).
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