GBP6 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, ICC |
---|---|
Primary Accession | Q6ZN66 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 72kDa |
Dilution | IHC-P (5 µg/ml), WB (0.5-1 µg/ml), |
Gene ID | 163351 |
---|---|
Other Names | Guanylate-binding protein 6, GTP-binding protein 6, GBP-6, Guanine nucleotide-binding protein 6, GBP6 |
Target/Specificity | Human GBP6. GBP6 antibody is predicted to not cross-react with other GBP family members. |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | GBP6 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GBP6 |
---|---|
Function | Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens, such as bacterial pathogens Listeria monocytogenes and Mycobacterium bovis BCG as well as the protozoan pathogen Toxoplasma gondii (By similarity). Confers protection to several pathogens, including the bacterial pathogens Listeria monocytogenes and Mycobacterium bovis BCG as well as the protozoan pathogen Toxoplasma gondii (By similarity). |
Cellular Location | Cytoplasmic vesicle {ECO:0000250|UniProtKB:A0A0G2JDV3} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Binds GTP, GDP and GMP.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Gregory S.G.,et al.Nature 441:315-321(2006).
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