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GSC / Goosecoid Antibody (clone 2C1)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P56915 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2C1 |
| Calculated MW | 28kDa |
| Dilution | IHC-P (3-10 µg/ml) |
| Gene ID | 145258 |
|---|---|
| Other Names | Homeobox protein goosecoid, GSC |
| Target/Specificity | Human GSC |
| Reconstitution & Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | GSC / Goosecoid Antibody (clone 2C1) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GSC |
|---|---|
| Function | Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals.
References
Blum M.,et al.Genomics 21:388-393(1994).
Guo J.H.,et al.Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
Parry D.A.,et al.Am. J. Hum. Genet. 93:1135-1142(2013).
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