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ZIC3 Antibody (aa178-189)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E |
|---|---|
| Primary Accession | O60481 |
| Reactivity | Human, Mouse, Rat, Rabbit, Monkey, Horse, Bovine, Guinea Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 51kDa |
| Dilution | ELISA (1:64000), IHC-P (5 µg/ml), |
| Gene ID | 7547 |
|---|---|
| Other Names | Zinc finger protein ZIC 3, Zinc finger protein 203, Zinc finger protein of the cerebellum 3, ZIC3, ZNF203 |
| Target/Specificity | Human ZIC3. This antibody is expected to NOT cross-react with other ZIC proteins. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | ZIC3 Antibody (aa178-189) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZIC3 |
|---|---|
| Synonyms | ZNF203 |
| Function | Acts as a transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC- 3'. |
| Cellular Location | Nucleus. Cytoplasm. Note=Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity) Translocation to the nucleus requires KPNA1 or KPNA6. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.
References
Gebbia M.,et al.Nat. Genet. 17:305-308(1997).
Salichs E.,et al.PLoS Genet. 5:E1000397-E1000397(2009).
Ross M.T.,et al.Nature 434:325-337(2005).
Zhu L.,et al.Hum. Mutat. 29:99-105(2008).
Bedard J.E.,et al.PLoS ONE 6:E23755-E23755(2011).
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