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DNAJC5 / CSP Antibody (aa177-191)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9H3Z4 |
| Reactivity | Human, Mouse, Rat, Rabbit, Monkey, Chicken, Horse, Bovine, Guinea Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 22kDa |
| Dilution | ELISA (1:64000), IHC-P (5 µg/ml), WB (0.5-1.5 µg/ml) |
| Gene ID | 80331 |
|---|---|
| Other Names | DnaJ homolog subfamily C member 5, Cysteine string protein, CSP, DNAJC5, CSP |
| Target/Specificity | Human DNAJC5 / CSP |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | DNAJC5 / CSP Antibody (aa177-191) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DNAJC5 (HGNC:16235) |
|---|---|
| Function | Acts as a general chaperone in regulated exocytosis (By similarity). Acts as a co-chaperone for the SNARE protein SNAP-25 (By similarity). Involved in the calcium-mediated control of a late stage of exocytosis (By similarity). May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity). |
| Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q29455}. Membrane {ECO:0000250|UniProtKB:Q29455}; Lipid-anchor {ECO:0000250|UniProtKB:Q29455}. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane {ECO:0000250|UniProtKB:Q29455}. Melanosome. Cell membrane. Note=The association with membranes is regulated by palmitoylation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). {ECO:0000250|UniProtKB:Q29455, ECO:0000269|PubMed:17081065} |
| Tissue Location | Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity).
References
Coppola T.,et al.FEBS Lett. 391:269-272(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Hattori A.,et al.DNA Res. 7:357-366(2000).
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