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LMTK3 Antibody (aa1251-1300)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q96Q04 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 154kDa |
| Dilution | ELISA (1:20000), IHC-P (10 µg/ml), WB (1:500-1:1000) |
| Gene ID | 114783 |
|---|---|
| Other Names | Serine/threonine-protein kinase LMTK3, 2.7.11.1, Lemur tyrosine kinase 3, LMTK3, KIAA1883, TYKLM3 |
| Target/Specificity | LMTK3 Antibody detects endogenous levels of total LMTK3 protein. |
| Reconstitution & Storage | Store at -20°C for up to one year. |
| Precautions | LMTK3 Antibody (aa1251-1300) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LMTK3 |
|---|---|
| Synonyms | KIAA1883, TYKLM3 |
| Function | Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity). |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:Q5XJV6}; Single- pass membrane protein {ECO:0000250|UniProtKB:Q5XJV6}. Cell projection, axon {ECO:0000250|UniProtKB:Q5XJV6}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q5XJV6}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q5XJV6}. Note=Punctate pattern in cell projections |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Nagase T.,et al.DNA Res. 8:179-187(2001).
Grimwood J.,et al.Nature 428:529-535(2004).
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