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CD20 Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P11836 |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 33kDa |
| Dilution | IHC-P (2-2.5 µg/ml), WB (3-5 µg/ml), |
| Gene ID | 931 |
|---|---|
| Other Names | B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20 |
| Target/Specificity | Human CD20 / MS4A1 |
| Reconstitution & Storage | Store vial at -20 C or below prior to opening. For extended storage, aliquot contents and freeze at -20 C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use. |
| Precautions | CD20 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MS4A1 |
|---|---|
| Synonyms | CD20 |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:12920111, PubMed:3925015, PubMed:7684739). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:12920111, PubMed:18474602, PubMed:7684739). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor. Note=Constitutively associated with membrane rafts. |
| Tissue Location | Expressed on B-cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This protein may be involved in the regulation of B-cell activation and proliferation.
References
Stamenkovic I.,et al.J. Exp. Med. 167:1975-1980(1988).
Tedder T.F.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:208-212(1988).
Einfeld D.A.,et al.EMBO J. 7:711-717(1988).
Tedder T.F.,et al.J. Immunol. 142:2560-2568(1989).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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