PMP70 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IHC-P |
---|---|
Primary Accession | P28288 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 75kDa |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 5825 |
---|---|
Other Names | ATP-binding cassette sub-family D member 3, 70 kDa peroxisomal membrane protein, PMP70, ABCD3, PMP70, PXMP1 |
Reconstitution & Storage | Store at -20°C for up to one year. |
Precautions | PMP70 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ABCD3 (HGNC:67) |
---|---|
Function | Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long- chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched- chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation (PubMed:11248239, PubMed:25168382, PubMed:24333844, PubMed:29397936). Has fatty acyl-CoA thioesterase and ATPase activities (PubMed:29397936). Probably hydrolyzes fatty acyl- CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes (By similarity). Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation (PubMed:25944712, PubMed:24333844). |
Cellular Location | Peroxisome membrane; Multi-pass membrane protein |
Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.
References
Gaertner J.,et al.Nat. Genet. 1:16-23(1992).
Kamijo K.,et al.Biochim. Biophys. Acta 1129:323-327(1992).
Gaertner J.,et al.Genomics 48:203-208(1998).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.