TMEM59L Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q9UK28 |
Other Accession | 25789 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37619 Da |
Dilution | IF (20 µg/ml), IHC-P (5 µg/ml), WB (1 µg/ml), |
Gene ID | 25789 |
---|---|
Other Names | TMEM59L, C19orf4, Transmembrane protein 59-like, BSMAP |
Target/Specificity | Human TMEM59L / C19orf4. Multiple isoforms of TMEM59L are known to exist. TMEM59L antibody is predicted to not cross-react TMEM59. |
Reconstitution & Storage | PBS, 0.02% sodium azide. Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | TMEM59L Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TMEM59L |
---|---|
Synonyms | BSMAP, C19orf4 |
Function | Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. |
Cellular Location | Golgi apparatus membrane; Single-pass type I membrane protein |
Tissue Location | Expressed preferentially at high level in the brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding.
References
Elson G.C.A.,et al.Biochem. Biophys. Res. Commun. 264:55-62(1999).
Ullrich S.,et al.J. Biol. Chem. 285:20664-20674(2010).
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