PPP1R11 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | O60927 |
Other Accession | 6992 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 13953 Da |
Dilution | IHC-P (5 µg/ml), |
Gene ID | 6992 |
---|---|
Other Names | PPP1R11, HCG-V, HCG V, Inhibitor-3, HCGV, TCTEX5, IPP3, TCTE5 |
Target/Specificity | Human PPP1R11 |
Reconstitution & Storage | PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
Precautions | PPP1R11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PPP1R11 |
---|---|
Synonyms | HCGV, TCTE5 |
Function | Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901). Inhibitor of protein phosphatase 1 (PubMed:9843442). |
Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Inhibitor of protein phosphatase 1.
References
Giffon T.,et al.Immunogenetics 44:331-339(1996).
Lepourcelet M.,et al.Genomics 37:316-326(1996).
Shiina S.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
Shiina T.,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
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