Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
GYPA / CD235a / Glycophorin A Antibody (clone YTH89.1)
Rat Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, FC |
|---|---|
| Primary Accession | P02724 |
| Other Accession | 2993 |
| Reactivity | Human |
| Host | Rat |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Clone Names | YTH89.1 |
| Calculated MW | 16430 Da |
| Dilution | Flo (1:10 - 1:25), IHC-Fr (1:100 - 1:1000), IHC-P (2.5 - 5 µg/ml), |
| Gene ID | 2993 |
|---|---|
| Other Names | GYPA, CD235a, CD235a antigen, Glycophorin A (MN blood group), Glycophorin A, GPA, Glycophorin-A, GPA, GPErik, GPSAT, Glycophorin MiV, Glycophorin SAT, HGpMiX, HGpMiXI, HGpMiV, HGpSta(C), Glycophorin MiI, GpMiIII, MN, HGpMiIII, MN sialoglycoprotein, S ... |
| Reconstitution & Storage | PBS, 0.09% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GYPA / CD235a / Glycophorin A Antibody (clone YTH89.1) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GYPA (HGNC:4702) |
|---|---|
| Function | Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane (PubMed:35835865). Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein Note=Appears to be colocalized with SLC4A1 |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).
References
Siebert P.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:1665-1669(1986).
Tate C.G.,et al.Biochem. J. 254:743-750(1988).
Kudo S.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:4619-4623(1989).
Jawad K.,et al.Nucleic Acids Res. 18:5829-5836(1990).
Kudo S.,et al.J. Biochem. 116:183-192(1994).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
