VNN1 Antibody (clone 4E11)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | O95497 |
Other Accession | 8876 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2a,k |
Clone Names | 4E11 |
Calculated MW | 57012 Da |
Dilution | IHC-P (10 µg/ml), |
Gene ID | 8876 |
---|---|
Other Names | VNN1, HDLCQ8, Pantetheinase, Pantetheine hydrolase, Vanin-1, Tiff66, Vanin 1, Vannin 1 |
Target/Specificity | Human VNN1 |
Reconstitution & Storage | PBS, pH 7.4. Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | VNN1 Antibody (clone 4E11) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | VNN1 |
---|---|
Function | Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. |
Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor |
Tissue Location | Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
References
Galland F.,et al.Genomics 53:203-213(1998).
Prehn S.,et al.Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Maras B.,et al.FEBS Lett. 461:149-152(1999).
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