FGF19 Antibody (clone FG98-6)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | O95750 |
Other Accession | 9965 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2b,k |
Clone Names | FG98-6 |
Calculated MW | 24003 Da |
Dilution | ELISA (1:500 - 1:1000), IHC-P (15 µg/ml), WB (1:500 - 1:1000), |
Gene ID | 9965 |
---|---|
Other Names | FGF19, Fibroblast growth factor 19, FGF-19 |
Target/Specificity | Recognizes human FGF-19. Detects a band of ~25kDa by Western blot. |
Reconstitution & Storage | PBS, pH 7.4, no preservatives. Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. |
Precautions | FGF19 Antibody (clone FG98-6) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FGF19 |
---|---|
Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. |
Cellular Location | Secreted. |
Tissue Location | Expressed in fetal brain, cartilage, retina, and adult gall bladder. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
References
Nishimura T.,et al.Biochim. Biophys. Acta 1444:148-151(1999).
Xie M.-H.,et al.Cytokine 11:729-735(1999).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.