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Anti-TUSC3 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
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- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P, IF, ICC |
|---|---|
| Primary Accession | Q13454 |
| Predicted | Human, Monkey, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39676 Da |
| Dilution | ICC (1:100 - 1:500), IF, IHC-P (1:100), WB (1:500 - 1:1000) |
| Gene ID | 7991 |
|---|---|
| Alias Symbol | TUSC3 |
| Other Names | TUSC3, D8S1992, M33, MRT7, N33, OST3A, Tumor suppressor candidate 3, Protein N33, MRT22 |
| Target/Specificity | Recognizes endogenous levels of TUSC3 protein. |
| Reconstitution & Storage | PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
| Precautions | Anti-TUSC3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TUSC3 |
|---|---|
| Synonyms | N33 |
| Function | Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 467.50
Cat# ALS17338
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