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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-GBAS Antibody (clone 1B8)
Anti-GBAS Antibody (clone 1B8)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF |
|---|---|
| Primary Accession | O75323 |
| Predicted | Human, Mouse, Rat, Monkey, Dog |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone Names | 1B8 |
| Calculated MW | 33743 Da |
| Dilution | IF (1:100), IHC-P (10 µg/ml), WB (1:200 - 1:2000) |
| Gene ID | 2631 |
|---|---|
| Alias Symbol | GBAS |
| Other Names | GBAS, NIPSNAP2, Protein NipSnap homolog 2 |
| Target/Specificity | Human GBAS |
| Reconstitution & Storage | PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide Store at -20°C. Minimize freezing and thawing. |
| Precautions | Anti-GBAS Antibody (clone 1B8) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NIPSNAP2 {ECO:0000303|PubMed:30982665, ECO:0000312|HGNC:HGNC:4179} |
|---|---|
| Function | Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria (PubMed:30982665). Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2) (PubMed:30982665). |
| Cellular Location | Mitochondrion matrix |
| Tissue Location | Widely expressed (PubMed:9615231). Most abundant in heart and skeletal muscle (PubMed:9615231) |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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