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Anti-Prostaglandin D2 Receptor Antibody (N-Terminus)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q13258
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 40271 Da
Dilution IHC-P (15 - 20 µg/ml)
Additional Information
Gene ID 5729
Alias Symbol PTGDR
Other Names PTGDR, DP, Dp receptor, PGD receptor, Prostaglandin D2 receptor (DP), Prostanoid DP receptor, PTGDR1, PGD2 receptor, Prostaglandin DP receptor, AS1, ASRT1, Dp prostanoid receptor, DP1, Prostaglandin D2 receptor
Target/Specificity Human Prostaglandin D2 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-Prostaglandin D2 Receptor Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTGDR
Function Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). Involved in PLA2G3- dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes.
Research Areas
Citations (0)
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$ 467.50
Cat# ALS17524
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