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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-SDC1 / Syndecan 1 / CD138 Antibody
Anti-SDC1 / Syndecan 1 / CD138 Antibody
Mouse Anti Human Monoclonal Antibody
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- BACKGROUND
Application 
| IHC-P, IHC-F, FC |
|---|---|
| Primary Accession | P18827 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Calculated MW | 32462 Da |
| Dilution | Flo (1:1), IHC-Fr (1:100 - 1:500), IHC-P (1:100 - 1:500, 10 µg/ml) |
| Gene ID | 6382 |
|---|---|
| Alias Symbol | SDC1 |
| Other Names | SDC1, CD138 antigen, SDC, SYND1, Syndecan, Syndecan 1, Syndecan-1, CD138, Syndecan proteoglycan 1 |
| Target/Specificity | Recognizes a heparan sulfate rich membrane glycoprotein of 200kD known as Syndecan-1 (CD138). Syndecan functions as a receptor for collagen, fibronectin and thrombospondin. Stains all plasma cells and plasma cell lines. No staining of other leucocyte ... |
| Reconstitution & Storage | Protein G purified |
| Precautions | Anti-SDC1 / Syndecan 1 / CD138 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SDC1 (HGNC:10658) |
|---|---|
| Synonyms | SDC |
| Function | Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity). |
| Cellular Location | Membrane; Single-pass type I membrane protein. Secreted Secreted, extracellular exosome Note=Shedding of the ectodomain produces a soluble form |
| Tissue Location | Detected in placenta (at protein level) (PubMed:32337544). Detected in fibroblasts (at protein level) (PubMed:36213313). |
Research Areas
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Application Protocols
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$ 467.50
Cat# ALS17823
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