Anti-TSH Receptor / TSHR Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P16473 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 86830 Da |
Dilution | IHC-P (2.5 - 5 µg/ml) |
Gene ID | 7253 |
---|---|
Alias Symbol | TSHR |
Other Names | TSHR, CHNG1, HTSHR-I, LGR3, Thyrotrophin receptor, TSH-R, TSH receptor, Thyrotropin receptor |
Target/Specificity | Human TSH Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-TSH Receptor / TSHR Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TSHR |
---|---|
Synonyms | LGR3 |
Function | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Plays a central role in controlling thyroid cell metabolism (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein |
Tissue Location | Expressed in thyroide cells (at protein level) (PubMed:11847099). Expressed in the thyroid (PubMed:2610690) |
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