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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-KCNC1 / Kv3.1 Antibody (Internal)
Anti-KCNC1 / Kv3.1 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P48547 |
| Predicted | Human, Mouse, Rat, Rabbit, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 57942 Da |
| Dilution | IHC-P (1:100), WB (1:500 - 1:1000) |
| Gene ID | 3746 |
|---|---|
| Alias Symbol | KCNC1 |
| Other Names | KCNC1, KShIIIB, KV3.1, Raw2, Shaw22, KV4, NGK2 |
| Target/Specificity | Recognizes endogenous levels of Kv3.1 protein. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-KCNC1 / Kv3.1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KCNC1 {ECO:0000303|PubMed:8449507, ECO:0000312|HGNC:HGNC:6233} |
|---|---|
| Function | Voltage-gated potassium channel that opens in response to the voltage difference across the membrane and through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298, PubMed:35840580). The mechanism is time-dependent and inactivation is slow (By similarity). Plays an important role in the rapid repolarization of fast-firing brain neurons (By similarity). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well (By similarity). Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:P25122}. Presynaptic cell membrane {ECO:0000250|UniProtKB:P25122}. Note=Localizes in parallel fiber membranes, distributed on the perisynaptic and extrasynaptic membranes away from the active zones. {ECO:0000250|UniProtKB:P25122} |
Research Areas
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Application Protocols
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$ 467.50
Cat# ALS18413
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