Anti-CREM / ICER Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q03060 |
Predicted | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 37006 Da |
Dilution | IHC-P (1:100), WB |
Gene ID | 1390 |
---|---|
Alias Symbol | CREM |
Other Names | CREM, CREM-2, CREM 2alpha-b protein, CREM 2beta-a protein, HCREM-2, Inducible cAMP early repressor, ICER |
Target/Specificity | Human CREM / ICER |
Reconstitution & Storage | Affinity purified |
Precautions | Anti-CREM / ICER Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CREM (HGNC:2352) |
---|---|
Function | Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550). |
Cellular Location | Nucleus. |
Tissue Location | Expressed in testes (round spermatids) (at protein level). Isoform 14 is the major activator form in testes |
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