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CAB39 Antibody
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y376 |
| Other Accession | Q29RI6, NP_001124321.1, NP_001124322.1 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1,K |
| Clone/Animal Names | 198CT13.9.1 |
| Calculated MW | 39869 Da |
| Gene ID | 51719 |
|---|---|
| Other Names | Calcium-binding protein 39, MO25alpha, Protein Mo25, CAB39, MO25 |
| Target/Specificity | This CAB39 monoclonal antibody is generated from mouse immunized with CAB39 recombinant protein. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CAB39 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CAB39 |
|---|---|
| Synonyms | MO25 |
| Function | Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1. |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of STK11.
References
Zeqiraj, E., et al. Science 326(5960):1707-1711(2009)
Zeqiraj, E., et al. PLoS Biol. 7 (6), E1000126 (2009) :
ten Klooster, J.P., et al. Dev. Cell 16(4):551-562(2009)
Fogarty, S., et al. J. Biol. Chem. 284(1):77-84(2009)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
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