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ENOG Antibody
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P09104 |
| Other Accession | NP_001966.1 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b,k |
| Clone/Animal Names | 279CT17.1.1 |
| Calculated MW | 47269 Da |
| Gene ID | 2026 |
|---|---|
| Other Names | Gamma-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 2, Neural enolase, Neuron-specific enolase, NSE, ENO2 |
| Target/Specificity | This ENOG monoclonal antibody is generated from mouse immunized with ENOG recombinant protein. |
| Dilution | IHC~~1:2000 WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ENOG Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ENO2 |
|---|---|
| Function | Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium- dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). |
| Cellular Location | Cytoplasm. Cell membrane. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form |
| Tissue Location | The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.
References
Martins-de-Souza, D., et al. J Psychiatr Res 44(14):989-991(2010)
Mukhtarova, S.N. Georgian Med News 181, 49-54 (2010) :
Planche, V., et al. Ann. Biol. Clin. (Paris) 68(2):239-242(2010)
Chaves, M.L., et al. J Neuroinflammation 7, 6 (2010) :
Wijeyaratne, S.M., et al. Eur J Vasc Endovasc Surg 38(3):262-266(2009)
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