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GAST Antibody(Ascites)
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P01350 |
| Other Accession | NP_000796.1 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone/Animal Names | 486CT4.8.13.6 |
| Calculated MW | 11394 Da |
| Antigen Region | 49-78 aa |
| Gene ID | 2520 |
|---|---|
| Other Names | Gastrin, Gastrin-71, Gastrin component I, Gastrin-52, G52, Big gastrin, Gastrin component II, Gastrin-34, G34, Gastrin, Gastrin component III, Gastrin-17, G17, Gastrin-14, G14, Gastrin-6, G6, GAST, GAS |
| Target/Specificity | This GAST antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from human GAST. |
| Dilution | WB~~1:100~1600 E~~Use at an assay dependent concentration. |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GAST Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GAST |
|---|---|
| Synonyms | GAS |
| Function | Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq].
References
Kovac, S., et al. FEBS Lett. 584(21):4413-4418(2010)
Ferrand, A., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (1), G220-G227 (2010) :
El Ali, Z., et al. J. Endocrinol. Invest. 33(3):186-191(2010)
Huang, C.L., et al. Pharmacology 85(3):131-135(2010)
Leja, M., et al. Dig. Dis. Sci. 54(11):2377-2384(2009)
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