PIp1 Antibody (Center)
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | P60201 |
| Other Accession | P60202, P60203, P04116, P23289, Q8HXW7, Q712P7, P47789 |
| Reactivity | Human, Mouse, Rat |
| Predicted | Bovine, Chicken, Monkey, Pig, Rabbit |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgM |
| Clone/Animal Names | 538CT16.5.4 |
| Calculated MW | 30,077 Da |
| Antigen Region | 248-277 aa |
| Gene ID | 5354 |
|---|---|
| Other Names | Myelin proteolipid protein, PLP, Lipophilin, Plp1, Plp |
| Target/Specificity | This PIp1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 248-277 amino acids from the central region of human PIp1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PIp1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLP1 |
|---|---|
| Synonyms | PLP |
| Function | This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Myelin membrane. Note=Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat. |

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Provided below are standard protocols that you may find useful for product applications.
Background
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
References
Mayer, C.A., et al. Respir Physiol Neurobiol 169(3):303-314(2009)
Wang, E., et al. J. Cell. Biochem. 97(5):999-1016(2006)
Gudz, T.I., et al. J. Neurosci. 22(17):7398-7407(2002)
Boucher, S.E., et al. J. Neurosci. 22(5):1772-1783(2002)
Yamamoto, T., et al. Hum. Mutat. 14 (2), 182 (1999) :
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