TPIPb Antibody (C-term)(Ascites)
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q6XPS3 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone/Animal Names | 978CT6.1.4 |
| Calculated MW | 61112 Da |
| Gene ID | 93492 |
|---|---|
| Other Names | Phosphatidylinositol 3, 5-trisphosphate 3-phosphatase TPTE2, Lipid phosphatase TPIP, TPTE and PTEN homologous inositol lipid phosphatase, TPTE2, TPIP |
| Target/Specificity | Purified His-tagged TPIPb protein was used to produced this monoclonal antibody. |
| Dilution | WB~~1:5000 E~~Use at an assay dependent concentration. |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TPIPb Antibody (C-term)(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TPTE2 |
|---|---|
| Synonyms | TPIP {ECO:0000303|PubMed:11716755} |
| Function | Acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate. |
| Cellular Location | [Isoform 3]: Endoplasmic reticulum membrane; Multi-pass membrane protein [Isoform 4]: Cytoplasm |
| Tissue Location | Isoform 3 is expressed in testis, brain and stomach while isoform 4 seems to be testis-specific |

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Provided below are standard protocols that you may find useful for product applications.
References
Walker S.M., et al. Biochem. J. 360:277-283(2001).
Tapparel C., et al. Gene 323:189-199(2003).
Dunham A., et al. Nature 428:522-528(2004).
Mural R.J., et al. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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