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AGXT Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P21549 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1,k |
| Clone/Animal Names | 1739CT804.82.83.1 |
| Calculated MW | 43010 Da |
| Gene ID | 189 |
|---|---|
| Other Names | Serine--pyruvate aminotransferase, SPT, 2.6.1.51, Alanine--glyoxylate aminotransferase, AGT, 2.6.1.44, AGXT, AGT1, SPAT |
| Target/Specificity | This AGXT antibody is generated from a mouse immunized with a recombinant protein between 188-375 amino acids from the human AGXT. |
| Dilution | WB~~1:1000-1:2000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | AGXT Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AGXT (HGNC:341) |
|---|---|
| Synonyms | AGT1, SPAT |
| Function | Peroxisomal aminotransferase that catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification (PubMed:10960483, PubMed:12777626, PubMed:24055001, PubMed:23229545, PubMed:26149463). Also catalyzes the transamination between L-serine and pyruvate and contributes to gluconeogenesis from the L-serine metabolism (PubMed:10347152). |
| Cellular Location | Peroxisome |
| Tissue Location | Liver. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Nishiyama K.,et al.Eur. J. Biochem. 194:9-18(1990).
Purdue P.E.,et al.J. Cell Biol. 111:2341-2351(1990).
Takada Y.,et al.Biochem. J. 268:517-520(1990).
Purdue P.E.,et al.Genomics 10:34-42(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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