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GSTA1 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P08263 |
| Reactivity | Human, Rat |
| Predicted | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1,κ |
| Clone/Animal Names | 2128CT386.77.4 |
| Calculated MW | 25631 Da |
| Gene ID | 2938 |
|---|---|
| Other Names | Glutathione S-transferase A1, 2.5.1.18, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, Glutathione S-transferase A1, N-terminally processed, GSTA1 |
| Target/Specificity | This GSTA1 antibody is generated from a mouse immunized with a recombiant protein from the human region of human GSTA1. |
| Dilution | WB~~1:5000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GSTA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GSTA1 |
|---|---|
| Function | Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene- 3,17-dione and may therefore play an important role in hormone biosynthesis (PubMed:11152686). Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)- hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid (PubMed:16624487). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Liver. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
References
Tu C.-P.D.,et al.Biochem. Biophys. Res. Commun. 141:229-237(1986).
Rhoads D.M.,et al.Biochem. Biophys. Res. Commun. 145:474-481(1987).
Tu C.-P.D.,et al.Biochem. Soc. Trans. 15:734-736(1987).
Board P.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:2377-2381(1987).
Rozen F.,et al.Arch. Biochem. Biophys. 292:589-593(1992).
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