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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Phospho Antibodies   >   Testicular Receptor 2 (TR2) Antibody   

Testicular Receptor 2 (TR2) Antibody

Rabbit polyclonal antibody.

  • WB - Testicular Receptor 2 (TR2) Antibody AN1181
    Western blot of rat testes lysate showing specific immunolabelingof the ~ 64k TR2 protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q505F1
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 64 KDa
Additional Information
Gene ID 22025
Gene Name NR2C1
Other Names Nuclear receptor subfamily 2 group C member 1, Orphan nuclear receptor TR2, Testicular receptor 2, mTR2, Nr2c1 {ECO:0000312|MGI:MGI:1352465}
Target/Specificity Fusion protein from the N-terminal region of mouse TR2.
Dilution WB~~ 1:1000
Format neat serum.
Antibody Specificity Specific for the ~64 kDa TR2 protein in Western blots of testes and nuclear extracts from MEL cell lines.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTesticular Receptor 2 (TR2) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
ShippingBlue Ice
Research Areas
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Testicular receptor 2 (TR2) is a member of the orphan nuclear receptor family. It is widely expressed at a low level throughout the adult testis. TR2 represses transcription and binds DNA directly interacting with HDAC3 and HDAC4 via DNA-binding domains (Franco et al., 2003). TR2 has also been implicated in regulation of estrogen receptor activity in mammary glands (Hun et al., 2002). In addition, TR2 has recently been shown to form a heterodimer with TR4 that can bind to the direct repeat 6 element of the hepatitis B virus (HBV) enhancer II region thus suppressing HBV gene expression (Lin et al., 2008).


Franco PJ, Li G, Wei LN (2003) Interaction of nuclear receptor
Hu YC, Shyr CR, Che W, Mu XM, Kim E, Chang C. (2002) Suppression of estrogen receptor-mediated transcription a
Lin TJ, Yang RY, Lee HJ. (2008) Collective repression of the hepati
Tanabe O, McPhee D, Kobayashi S, Shen Y, Brandt W, Jiang X, Campbell AD, Chen YTChang C, Yamamoto M, Tanimoto K, Engel JD. “Embryonic and fetal beta-globin gene
repression by the orphan nuclear receptors, TR2 and TR4.” EMBO J. 2007, 26:2295-306.

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$ 310.00
Cat# AN1181
Availability: 7-10 days
Bulk Size

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