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Anti-LAMP1 Antibody

Our Anti-LAMP1 primary antibody from PhosphoSolutions is mouse monoclonal. It detects human LAMP1 an

     
  •  - Anti-LAMP1 Antibody AN1434
    Immunolabeling of HeLa cells showing vesicular staining of LAMP1 protein (cat. 1030-LAMP1, red, 1:2000) accumulated in swollen lysosomes, while Anti-Vimentin (cat. 2105-VIM, green, 1:500) specifically labels the intermediate filament network in these cells. The blue stain is DAPI to reveal nuclear DNA.
    detail
  •  - Anti-LAMP1 Antibody AN1434
    Western blot of HeLa cell lysate showing specific immunolabeling of the ~100 kDa LAMP1 protein.
    detail
  •  - Anti-LAMP1 Antibody AN1434
    Immunostaining of HeLa cells showing specific, strong cytoplasmic labeling of LAMP1 (cat. 1030-LAMP1, red, 1:2000) corresponding to lysosomes and late endosomes. Additional staining with Anti-Vimentin (cat. 2105-VIM, green, 1:500) specifically labeling the intermediate filament network. The blue stain is DAPI to reveal nuclear DNA.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P11279
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 5H6
Calculated MW 44882 Da
Additional Information
Gene ID 3916
Other Names CD107 antigen like family member A antibody, CD107 antigen-like family member A antibody, CD107a antibody, CD107a antigen antibody, LAMP 1 antibody, LAMP-1 antibody, LAMP1 antibody, LAMP1_HUMAN antibody, LAMPA antibody, LGP120 antibody, lgpA antibody, Lysosomal membrane glycoprotein 120KD antibody, Lysosomal Associated Membrane Protein 1 antibody, Lysosome associated membrane glycoprotein 1 antibody, Lysosome-associated membrane glycoprotein 1 antibody, Lysosome-associated membrane protein 1 antibody, OTTHUMP00000040663 antibody
Target/Specificity Lysosomal Associated Membrane Protein1 (LAMP1) is a protein that is localized primarily in lysosomes but may also be present on late endosomes and the plasma membrane. LAMP1 antibodies are therefore widely used as lysosome markers. It has recently been suggested that lysosomes are activated in microglia in the progression of multiple system atrophy (MSA) and thus play a key role in its pathology (Makioka et al., 2012).
Format Protein G Purified
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAnti-LAMP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
ShippingBlue Ice
Research Areas
Citations (0)
citation

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Background

Lysosomal Associated Membrane Protein1 (LAMP1) is a protein that is localized primarily in lysosomes but may also be present on late endosomes and the plasma membrane. LAMP1 antibodies are therefore widely used as lysosome markers. It has recently been suggested that lysosomes are activated in microglia in the progression of multiple system atrophy (MSA) and thus play a key role in its pathology (Makioka et al., 2012).

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$ 430.00
Cat# AN1434
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