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KSHV ORF26 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | F5HGN8 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2F6B8 |
| Isotype | IgG1 |
| Calculated MW | 34373 Da |
| Description | Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF26 open reading frames are juxtaposed and span from nucleotide (nt) 46933 to 47850 of the virus genome. Akula et al (2003) report it acts as a Capsid protein. |
| Immunogen | Purified recombinant fragment of KSHV ORF26 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 4961509 |
|---|---|
| Other Names | Triplex capsid protein VP23 homolog, ORF26 |
| Dilution | WB~~1/500 - 1/2000 IHC~~1:200~~1000 IF~~1:200~1000. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KSHV ORF26 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRX2 {ECO:0000255|HAMAP-Rule:MF_04019} |
|---|---|
| Function | Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly. |
| Cellular Location | Virion {ECO:0000255|HAMAP-Rule:MF_04019}. Host nucleus {ECO:0000255|HAMAP-Rule:MF_04019} |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
1. James J . Proc. Natl. Acad. Sci Vol. 1996. 93, pp. 14862-14867.
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$ 300.00
Cat# AO1034a
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