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FBLN2 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P98095 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 7H4F6; 3B9A11 |
| Isotype | IgG1 |
| Calculated MW | 126573 Da |
| Description | FBLN2: fibulin 2. This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Immunogen | Purified recombinant fragment of FBLN2 (aa180-440) expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 2199 |
|---|---|
| Other Names | Fibulin-2, FIBL-2, FBLN2 |
| Dilution | WB~~1/500 - 1/2000 E~~N/A |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FBLN2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FBLN2 |
|---|---|
| Function | Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108). |
| Cellular Location | Secreted, extracellular space, extracellular matrix |
| Tissue Location | Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
1. J Biol Chem. 1996 Aug 9;271(32):19489-96. 2. Eur J Hum Genet. 1996;4(5):292-5. 3. J Invest Dermatol. 1999 Jan;112(1):97-101. 4. Br J Dermatol. 2001 Aug;145(2):217-22.
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