LPA Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, E |
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Primary Accession | P08519.1 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 8F6A9; 8H5C5 |
Isotype | IgG1 |
Description | LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation. |
Immunogen | Purified recombinant fragment of LPA (4330-4521) expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Dilution | WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 |
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Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LPA Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
References
1. J Stroke Cerebrovasc Dis. 2007 Sep-Oct;16(5):220-4. 2. Clin Chim Acta. 2008 Jan;387(1-2):109-12.
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