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MESP1 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BRJ9 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 1A3 |
| Isotype | IgG1 |
| Calculated MW | 28.5kDa |
| Description | Mesp1 (mesoderm posterior 1) is a basic helix-loop-helix-type transcription factor, which along with its related proteins, has an essential role in both segmentation and rostro-caudal patterning of somites in the anterior pre-somitic mesoderm. Mesp1 is expressed in many of the precursors of the cardiovascular system and is known to play a role in the process of cardiac morphogenesis. |
| Immunogen | Purified recombinant fragment of human MESP1 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 55897 |
|---|---|
| Other Names | Mesoderm posterior protein 1, Class C basic helix-loop-helix protein 5, bHLHc5, MESP1, BHLHC5 |
| Dilution | WB~~1/500 - 1/2000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MESP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MESP1 |
|---|---|
| Synonyms | BHLHC5 |
| Function | Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
References
1. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3859-64. 2. Cell Stem Cell. 2008 Jul 3;3(1):69-84. 3. Circulation. 2008 Jul 29;118(5):507-17.
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