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ETV5 Antibody

Purified Mouse Monoclonal Antibody

     
  • WB - ETV5 Antibody AO1408a
    Figure 1: Western blot analysis using ETV5 mouse mAb against Jurkat (1), NIH/3T3 (2) and MCF-7 (3) cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P41161
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3H3
Isotype IgG1
Calculated MW 58kDa
Description ETS variant 5,transcription factor of the ETS family,divergent member of the winged helix-turn-helix superfamily,expressed in brain,placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.
Immunogen Purified recombinant fragment of human ETV5 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 2119
Other Names ETS translocation variant 5, Ets-related protein ERM, ETV5, ERM
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsETV5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ETV5
Synonyms ERM
Function Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'.
Cellular Location Nucleus.
Tissue Location Ubiquitous.
Research Areas
Citations (0)
citation

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References

1. Immunity. 2002 Oct;17(4):401-12. 2. Clin Cancer Res. 2004 Nov 1;10(21):7297-303. 3. J Hum Genet. 2009 Dec;54(12):727-31.

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$ 325.00
Cat# AO1408a
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