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GATA5 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BWX5 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 1B11 |
| Isotype | IgG1 |
| Calculated MW | 41kDa |
| Description | The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. |
| Immunogen | Purified recombinant fragment of human GATA5 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 140628 |
|---|---|
| Other Names | Transcription factor GATA-5, GATA-binding factor 5, GATA5 |
| Dilution | WB~~1/500 - 1/2000 E~~1/10000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GATA5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GATA5 (HGNC:15802) |
|---|---|
| Function | Transcription factor required during cardiovascular development (PubMed:23289003). Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity (By similarity). Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (PubMed:25543888). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
References
1. Clin Cancer Res. 2009 Jun 15;15(12):3990-7. 2. World J Gastroenterol. 2010 Mar 14;16(10):1201-8.
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