Mouse Monoclonal Antibody to AFAP1L2
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
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Primary Accession | Q8N4X5 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2H6D1 |
Isotype | Mouse IgG1 |
Calculated MW | 91.3kDa |
Description | AFAP1L2 (Actin Filament Associated Protein 1 Like 2) is a Protein Coding gene. GO annotations related to this gene include SH3 domain binding and protein tyrosine kinase activator activity. An important paralog of this gene is AFAP1.; |
Immunogen | Purified recombinant fragment of human AFAP1L2 (AA: 674-818) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application Note | ELISA: 1/10000 WB: 1/500 - 1/2000 FCM: 1/200 - 1/400 |
Gene ID | 84632 |
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Other Names | XB130; KIAA1914; CTB-1144G6.4 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Mouse Monoclonal Antibody to AFAP1L2 is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AFAP1L2 |
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Synonyms | KIAA1914, XB130 |
Function | May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. |
Cellular Location | Cytoplasm. |
Tissue Location | Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas. |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Int J Clin Exp Pathol. 2015 May 1;8(5):5300-8. ; 2.PLoS One. 2013;8(3):e59057.;
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