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GRIK5
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | Q16478 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 4G5H8 |
| Isotype | Mouse IgG1 |
| Calculated MW | 109.3kDa |
| Immunogen | Purified recombinant fragment of human GRIK5 (AA: extra 21-166) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 2901 |
|---|---|
| Other Names | KA2; EAA2; GRIK2; GluK5 |
| Dilution | WB~~ 1/500 - 1/2000 IHC~~1:100~500 ICC~~N/A E~~ 1/10000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GRIK5 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRIK5 |
|---|---|
| Synonyms | GRIK2 |
| Function | Ionotropic glutamate receptor that functions as a cation- permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Cannot form functional channels on its own and produces channel activity only in heteromeric assembly with GRIK1 and GRIK2 subunits (PubMed:1321949, PubMed:14511640, PubMed:8730589). Can form functional heteromeric receptors with GRIK3 (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q61626}; Multi-pass membrane protein. Presynaptic cell membrane {ECO:0000250|UniProtKB:Q61626}; Multi-pass membrane protein. Note=Association with GRIK2 is required for its cell membrane localization and channel activity |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
1.EMBO J. 2013 Feb 20;32(4):496-510.2.Psychiatry Res. 2006 Jan 30;141(1):39-51.
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