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CD269
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | Q02223 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 1D12G9 |
| Isotype | Mouse IgG1 |
| Calculated MW | 20.2kDa |
| Immunogen | Purified recombinant fragment of human BCMA (AA: QMAGQCSQNEYFDSLc) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 608 |
|---|---|
| Other Names | BCMA; TNFRSF17; BCM; TNFRSF13A |
| Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 FCM~~ 1/200 - 1/400 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CD269 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNFRSF17 |
|---|---|
| Synonyms | BCM, BCMA |
| Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
| Cellular Location | Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein Note=Perinuclear Golgi-like structures |
| Tissue Location | Expressed in mature B-cells, but not in T-cells or monocytes |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
1.Lupus. 2016 May;25(6):582-92. 2.Crit Rev Immunol. 2012;32(4):287-305.
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