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CD193
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | P51677 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 8E9H10 |
| Isotype | Mouse IgG1 |
| Calculated MW | 41kDa |
| Immunogen | Purified recombinant fragment of human CD193 (AA: extra mix) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 1232 |
|---|---|
| Other Names | CKR3; CCR3; CMKBR3; CC-CKR-3 |
| Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 FCM~~1/200 - 1/400 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CD193 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCR3 |
|---|---|
| Synonyms | CMKBR3 |
| Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064). Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed:8676064). In addition acts as a possible functional receptor for NARS1 (PubMed:30171954). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | In eosinophils as well as trace amounts in neutrophils and monocytes. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
1.J Dermatol Sci. 2013 Jul;71(1):12-21.2.Am J Clin Pathol. 2013 Sep;140(3):293-300.
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