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CD137
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | Q07011 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 4C1A9 |
| Isotype | Mouse IgG1 |
| Calculated MW | 27.9kDa |
| Immunogen | Purified recombinant fragment of human CD137 (AA: extra 24-186) expressed in HEK293 cells. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 3604 |
|---|---|
| Other Names | TNFRSF9; ILA; 4-1BB; CDw137 |
| Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CD137 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNFRSF9 |
|---|---|
| Synonyms | CD137, ILA |
| Function | Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed on the surface of activated T-cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
1.Clin Cancer Res. 2014 Jan 1;20(1):44-55.2.Cancer Res. 2013 Jan 15;73(2):652-61.
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