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GRM8
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | O00222 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 4C1C1 |
| Isotype | Mouse IgG1 |
| Calculated MW | 101.7kDa |
| Immunogen | Purified recombinant fragment of human GRM8 (AA: extra 440-583) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 2918 |
|---|---|
| Other Names | GLUR8; mGlu8; GPRC1H; MGLUR8 |
| Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GRM8 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRM8 |
|---|---|
| Synonyms | GPRC1H, MGLUR8 |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
1.Hereditas. 2014 Dec;151(6):140-4. 2.Am J Med Genet B Neuropsychiatr Genet. 2009 Apr 5;150B(3):359-68.
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