PCDP1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, E |
---|---|
Primary Accession | Q4G0U5 |
Other Accession | NP_001025167.2 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 96891 Da |
Antigen Region | 787-816 aa |
Gene ID | 200373 |
---|---|
Other Names | Cilia- and flagella-associated protein 221 {ECO:0000312|HGNC:HGNC:33720}, Primary ciliary dyskinesia protein 1, CFAP221 (HGNC:33720) |
Target/Specificity | This PCDP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 787-816 amino acids from the C-terminal region of humanPCDP1. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PCDP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CFAP221 (HGNC:33720) |
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Function | May play a role in cilium morphogenesis. |
Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm {ECO:0000250|UniProtKB:A9Q751}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A9Q751}. Note=Localizes to the manchette in elongating spermatids in a SPAG17-dependent manner {ECO:0000250|UniProtKB:A9Q751} |
Tissue Location | Expressed in ciliated respiratory epithelial cells and brain ependymal cells (at protein level) |

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Provided below are standard protocols that you may find useful for product applications.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008)
Lee, L., et al. Mol. Cell. Biol. 28(3):949-957(2008)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)

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