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> home > Products > Primary Antibodies > Antibody Collections > Catalog Updated > HHLA2 Antibody (N-term)
HHLA2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q9UM44 |
| Other Accession | NP_009003.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46850 Da |
| Antigen Region | 58-87 aa |
| Gene ID | 11148 |
|---|---|
| Other Names | HERV-H LTR-associating protein 2, Human endogenous retrovirus-H long terminal repeat-associating protein 2, HHLA2 |
| Target/Specificity | This HHLA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids of human HHLA2. |
| Dilution | WB~~1:2000 IHC-P~~1:25 FC~~1:25 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HHLA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HHLA2 |
|---|---|
| Function | Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed at high levels in colon, kidney, testis, lung and pancreas, and at lower levels in small intestine, liver and skeletal muscle. In immune cells, highly expressed in B-cells, dendritic cells and macrophages. Not detected in T-cells |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Mager, D.L., et al. Genomics 59(3):255-263(1999)
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$ 150.00
$ 385.00
Cat# AP10650a
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