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TJAP1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q5JTD0 |
| Other Accession | Q9DCD5, NP_001139488.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 61821 Da |
| Antigen Region | 144-171 aa |
| Gene ID | 93643 |
|---|---|
| Other Names | Tight junction-associated protein 1, Protein incorporated later into tight junctions, Tight junction protein 4, TJAP1, PILT, TJP4 |
| Target/Specificity | This TJAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-171 amino acids from the N-terminal region of human TJAP1. |
| Dilution | IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TJAP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TJAP1 (HGNC:17949) |
|---|---|
| Function | Plays a role in regulating the structure of the Golgi apparatus. |
| Cellular Location | Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q9DCD5}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q9DCD5}. Cell membrane {ECO:0000250|UniProtKB:Q9DCD5}; Peripheral membrane protein. Note=Recruited to tight junctions (TJ) during late stages of maturation of the TJ complexes. Excluded from adherens junctions and desmosomes. {ECO:0000250|UniProtKB:Q9DCD5} |
| Tissue Location | Ubiquitously expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a tight junction-associated protein. Incorporation of the encoded protein into tight junctions occurs at a late stage of formation of the junctions. The encoded protein localizes to the Golgi and may function in vesicle trafficking. Alternatively spliced transcript variants have been described. A related pseudogene exists on the X chromosome. [provided by RefSeq].
References
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Kawabe, H., et al. J. Biol. Chem. 276(51):48350-48355(2001)
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