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CF153 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q96EU6 |
| Other Accession | Q3UFY0, A6QNR1, NP_149103.1 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29823 Da |
| Antigen Region | 230-259 aa |
| Gene ID | 88745 |
|---|---|
| Other Names | Ribosomal RNA processing protein 36 homolog, RRP36, C6orf153 |
| Target/Specificity | This CF153 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the C-terminal region of human CF153. |
| Dilution | FC~~1:10~50 IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CF153 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RRP36 |
|---|---|
| Synonyms | C6orf153 |
| Function | Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA. |
| Cellular Location | Nucleus, nucleolus. Note=Concentrated in the fibrillar region of the nucleolus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RRP36 functions at an early stage in the processing of 35S preribosomal RNA into the mature 18S species (Gerus et al., 2010 [PubMed 20038530]).
References
Gerus, M., et al. Mol. Cell. Biol. 30(5):1130-1144(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Comtesse, N., et al. Proc. Natl. Acad. Sci. U.S.A. 102(27):9601-9606(2005)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
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