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> home > Products > Primary Antibodies > Antibody Collections > Mitochondrion > SIAH3 Antibody (C-term)
SIAH3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IW03 |
| Other Accession | NP_942146.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 30660 Da |
| Antigen Region | 185-213 aa |
| Gene ID | 283514 |
|---|---|
| Other Names | Seven in absentia homolog 3, Siah-3, SIAH3 |
| Target/Specificity | This SIAH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the C-terminal region of human SIAH3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SIAH3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SIAH3 |
|---|---|
| Function | Negative regulator of PRKN translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dysfunctional depolarized mitochondria. |
| Cellular Location | Mitochondrion. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
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$ 365.00
$ 140.00
Cat# AP10915B
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