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BCL7A Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - BCL7A Antibody (N-term) AP10984a
    BCL7A Antibody (N-term) (Cat. #AP10984a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the BCL7A antibody detected the BCL7A protein (arrow).
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q4VC05
Other Accession Q5XH61, Q9CXE2, Q5XFY4, NP_001019979.1, NP_066273.1
Reactivity Human
Predicted Zebrafish, Mouse, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 22810 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 605
Other Names B-cell CLL/lymphoma 7 protein family member A, BCL7A
Target/Specificity This BCL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BCL7A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBCL7A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCL7A
Research Areas
Citations (0)
citation

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Background

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.

References

Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Liang, X.S., et al. Br. J. Haematol. 146(4):418-423(2009)
Morton, L.M., et al. Cancer Epidemiol. Biomarkers Prev. 18(4):1259-1270(2009)
Carbone, A., et al. Genes Chromosomes Cancer 47(12):1067-1075(2008)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)

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$ 182.50
$ 70.00
Cat# AP10984a
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